Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4624)
Related Products (4624)
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5-Methoxyresorcinol
0 Images5-Methoxyresorcinol is a model molecule of the A ring of flavonoids, specifically simulating the chemical behavior of the resorcinol-type A ring found in catechins. 5-Methoxyresorcinol exhibits extremely low reactivity of tocopherol. 5-Methoxyresorcinol hardly inhibits cholesteryl ester transfer protein (CETP).
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(2S,4S)-1-(tert-Butoxycarbonyl)-4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidine-2-carboxylic acid
0 ImagesCat. No.: HY-42841CAS No.: 1821705-03-6(2S,4S)-1-(tert-Butoxycarbonyl)-4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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(2R,7aS)-Isopropyl 2-fluorohexahydro-1H-pyrrolizine-7a-carboxylate
0 Images(2R,7aS)-Isopropyl 2-fluorohexahydro-1H-pyrrolizine-7a-carboxylate is a drug intermediate for synthesis of various active compounds.
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Hydroquinone diacetate
0 ImagesHydroquinone diacetate (1,4-Diacetoxybenzene) is a diester product and also a commonly used synthetic intermediate for agrochemicals and fine chemicals. Hydroquinone diacetate can be produced via the acetylation of hydroquinone (HY-B0951) with acetic anhydride.
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Poly(methyl methacrylate)
0 ImagesCat. No.: HY-W391506CAS No.: 9011-14-7Synonyms: Poly(methyl methacrylate), beads; PMMAPoly (methyl methacrylate) (Poly(methyl methacrylate), beads; PMMA) is an amorphous glassy acrylic thermoplastic polymer belonging to the acrylate family, synthesized from methyl methacrylate monomers. Poly (methyl methacrylate) drives biochemical processes including free volume expansion induced by inelastic deformation, yield stress and strain softening regulated by physical aging, acid hydrolysis to polymethacrylic acid, multi-stage combustion, oxygen-dependent thermal decomposition, primary amine-mediated polypentanimide formation, and grafting/crosslinking-based copolymer and composite formation. Poly (methyl methacrylate) exhibits histocompatibility, low toxicity, low inflammatory potential, and fracture resistance; it can form functional blends and composites for biomedical and dental applications; it also allows performance-enhancing chemical and mechanical modifications. Poly (methyl methacrylate) is applicable to studies related to cranial repair.
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(S)-Pregabalin methyl ester hydrochloride
0 ImagesCat. No.: HY-W101682CAS No.: 714230-22-5(S)-Pregabalin methyl ester hydrochloride is a methyl ester form of Pregabalin.
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1-Boc-3-(hydroxymethyl)pyrrolidine
0 ImagesCat. No.: HY-60218CAS No.: 114214-69-61-Boc-3-(hydroxymethyl)pyrrolidine is an intermediate. 1-Boc-3-(hydroxymethyl)pyrrolidine can be used to synthesize a FGFR1/2/3/4 inhibitor (Compound 2). 1-Boc-3-(hydroxymethyl)pyrrolidine can be used in cancer research.
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4-Bromo-6-fluoro-1H-indazole
0 Images4-Bromo-6-fluoro-1H-indazole is a drug synthesis intermediate that can be used to synthesize an inhibitor of hematopoietic progenitor kinase 1 (hpk1).
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N-(Diphenylmethylene)glycine tert-butyl ester
0 ImagesN-(Diphenylmethylene)glycine tert-butyl ester is a protected glycine derivative. N-(Diphenylmethylene)glycine tert-butyl ester undergoes enantioselective alkylation to produce α-alkyl-α-amino acid derivatives.
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ADT-1004
0 ImagesADT-1004 is an orally active prodrug of ADT-007 (HY-157887). ADT-007 is a reversible, highly potent and selective pan-RAS inhibitor that binds to the nucleotide-free conformation of RAS proteins and blocks their GTP activation, thereby inhibiting the downstream MAPK and AKT signaling pathways. ADT-1004 can be used for the research of pancreatic ductal adenocarcinoma.
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Cyclomarin monomer-2
0 ImagesCat. No.: HY-P11498Cyclomarin monomer-2 (Compound 10), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-2 binds to the Mtb ClpC1 protein with a KD of 4.0 nM. The MIC of Cyclomarin monomer-2 against the Mtb H37Rv standard strain is 3.1 μM. Cyclomarin monomer-2 can be used as a key intermediate in the development of Homo-BacPROTACs.
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L-Guluronic acid sodium salt
0 ImagesL-Guluronic acid sodium salt is an uronic acid that can produce D-glucosaccharic acid on oxidation.
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3,3-Dimethylglutaric acid
0 Images3,3-Dimethylglutaric acid is an organic acid derivative and a candidate serum biomarker for sheep cystic echinococcosis. The serum level of 3,3-Dimethylglutaric acid increases significantly in sheep infected with Echinococcus granulosus. 3,3-Dimethylglutaric acid can serve as a ligand to synthesize metal complexes. 3,3-Dimethylglutaric acid is applicable to the research of cystic echinococcosis.
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2-(Chloromethyl)pyridine hydrochloride
0 ImagesSynonyms: Picolyl chloride hydrochloride2-(Chloromethyl)pyridine (Picolyl chloride) hydrochloride is an alkylating agent that can be used in organic synthesis reactions.
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42-(2-Tetrazolyl)rapamycin
0 ImagesCat. No.: HY-12424ACAS No.: 221877-56-142-(2-Tetrazolyl)rapamycin is a proagent compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.
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Methyl 3-aminopropanoate hydrochloride
0 ImagesSynonyms: β-Alanine methyl ester hydrochlorideMethyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is a β-alanine derivative with antioxidant activity. Methyl 3-aminopropanoate hydrochloride reduces oxidation-related changes in Glycine max soybean oil and degummed Glycine max soybean oil at frying temperatures, including the loss of olefinic protons and bis-allylic protons as well as the formation of polymerized triglycerides. Methyl 3-aminopropanoate hydrochloride contributes to the synthesis of the Bcl-2 inhibitor probe Nap-4.
